Elaine Shuo Feng
PhD MPH
Senior Epidemiologist and Statistician
Since 2012, Dr Elaine Feng have been working as an infectious disease epidemiologist, and has joined the Oxford Vaccine Group as a epidemiologist/statistician since September 2019. Elaine's research primarily focuses on four key areas: 1) test-negative study designs, 2) correlates of protection, 3) sero-epidemiology and 4) immunogenicity following vaccination. She has contributed significantly to the development of the correlates of protection of Oxford-AZ vaccine against SARS-CoV-2, and immunogenicity and efficacy of pneumococcal vaccines using network meta-analyses of individual participant data.
Elaine has obtained her BSc in Peking University, and MPH and PhD (under supervision by Prof Benjamin Cowling) in The University of Hong Kong. Her primary research interest is infectious disease epidemiology, in particular understanding immunogenicity, efficacy, effectiveness and impact of vaccines on infectious diseases.
Elaine has been involved in studies estimating the effectiveness of influenza vaccines using the test-negative design. She was participated in test-negative study data analysis in mainland China, Hong Kong and the US. She has also examined methodological issues in this study design including the impact of virus interference. Specifically, she investigated the intraseasonal waning rate of influenza vaccine effectiveness among hospitalised children in Hong Kong. Elaine has also involved in studies estimating influenza-associated disease burden in 30 provinces in China.
Key publications
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Rational use of face masks in the COVID-19 pandemic
Journal article
Feng S. et al, (2020), The Lancet Respiratory Medicine
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Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection.
Journal article
Feng S. et al, (2021), Nat Med, 27, 2032 - 2040
Recent publications
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Immunogenicity and seroefficacy of pneumococcal conjugate vaccines: a systematic review and network meta-analysis.
Journal article
Feng S. et al, (2024), Health Technol Assess, 28, 1 - 109
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Relationship between HLA genetic variations, COVID-19 vaccine antibody response, and risk of breakthrough outcomes
Journal article
PRIETO ALHAMBRA D. et al, (2024), Nature Communications
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Impact of Immunomodulatory Therapy on COVID-19 Vaccine Response in Patients with Autoimmune Inflammatory Rheumatic Diseases.
Journal article
Yap RXL. et al, (2024), Vaccines (Basel), 12
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Evaluating the impact of the biofire filmarray in childhood meningitis: an Observational Cohort Study
Journal article
Kadambari S. et al, (2024), Pediatric Infectious Disease Journal, 43, 345 - 349
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HLA Alleles, COVID-19 Vaccine Antibody Response and Real-World Breakthrough Outcomes
Preprint
Prieto-Alhambra D. et al, (2023)
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Immunogenicity and seroefficacy of 10-valent and 13-valent pneumococcal conjugate vaccines: a systematic review and network meta-analysis of individual participant data
Journal article
Feng S. et al, (2023), eClinicalMedicine, 61
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Number needed to vaccinate for COVID-19 booster doses: a valuable metric to inform vaccination strategies
Journal article
Feng S. et al, (2023), The Lancet Regional Health - Americas, 23, 100548 - 100548

