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Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.

Original publication

DOI

10.1016/j.micinf.2014.09.001

Type

Journal article

Journal

Microbes Infect

Publication Date

12/2014

Volume

16

Pages

1013 - 1021

Keywords

Drosophila melanogaster, RNA interference, Small interfering RNA, Viral infection, dsRNA, Animals, Drosophila, Gene Expression Regulation, Host-Pathogen Interactions, RNA Interference, RNA, Double-Stranded, RNA, Small Interfering, RNA, Viral